EVALUATION OF BLOOD GLUCOSE CONCENTRATION IN PATIENTS WITH DIABETES UNDERGOING TOOTH EXTRACTION AFTER ADMINISTRATION OF LOCAL ANESTHESIA WITH OR WITHOUT ADRENALINE

Abstract

The aim of this study was to determine the mean blood glucose concentration in patients with diabetes undergoing tooth extraction after administration of local anesthesia with or without adrenaline. A Randomized control trial (RCT) study was carried out from October 2015 to June 2016 in the Department of Oral & Maxillofacial Surgery of Islamic International Dental Hospital (IIDH) Islamabad on 60 diabetic patients undergoing tooth extraction requiring administration of local anesthesia. All patients were randomly divided into two equal groups that is group A (lignocaine without adrenaline) and group B (lignocaine with adrenaline). Blood glucose concentration measurements were taken 10 minutes before, 10 minutes and 20 minutes after administration of local anesthesia. Data were analyzed through SPSS version 17.

Patients age ranged from 25-75 years. Average age of patient was 64.59.86. There were 37% males and 23% females in both groups. The mean blood glucose concentration was increased in group B when compared to group A from 154 to 163.2mg/dl at 10 minutes. This increase in blood glucose concentration was statistically not significant (P ? 0.05). There was statistically significant (P<0.05) increase in blood glucose concentration in group B when compared to group A from 155.0 to 176.16 mg/dl at 20 minutes.

It was concluded that though 2% lignocaine with adrenaline is widely used local anesthetic, it should be cautiously used in type 2 diabetics.