COMPARISON OF CONNECTIVE TISSUE GRAFT AND XENOGENIC COLLAGEN MATRIX IN THE TREATMENT OF RT1 GINGIVAL RECESSIONS – A SYSTEMATIC REVIEW AND META ANALYSIS

Abstract

The aim of this systematic review was to compare the clinical efficacy using xenogenic collagen matrices vs autogenous connective tissue graft in the treatment of RT1 gingival recession (All) and multiple gingival recessions as reported from the systematic reviews. Methods: A literature search using pre-determined keywords and inclusion /exclusion criteria was carried out for published systematic reviews in the following electronic databases: PubMed, Google Scholar and Cochrane Database of Systematic Reviews (CDSR). Complete root coverage, mean root coverage, recession depth, keratinized tissue width, clinical attachment level gain and probing pocket depth reduction were measured. Pooled data were analyzed using fixed effect models and forest plots were constructed. Results: For gingival recessions (All) CTG showed superior results in achieving complete root coverage while XCM showed statistically significant (p < 0.0001) results only in achieving better keratinized tissue gain. Whereas no significant differences could be observed between the two in terms of mean root coverage, recession reduction, probing depth and clinical attachment gain. For multiple gingival recessions CTG showed statistically more significant results in obtaining complete root coverage, mean root coverage, recession depth reduction and keratinized tissue gain. On the opposite insignificant results were seen in achieving clinical attachment level gain and pocket depth reduction when both the grafts were compared. Conclusion: The CTG is highly recommended for patients with high demand for complete root coverage to resolve aesthetic problems and treat root hypersensitivity. However, XCM could be a viable alternative to CTG in achieving mean root coverage, reduction in recession depth, clinical attachment gain and reduction in probing depth in the treatment of gingival recessions (All). There is also a need for conducting more clinical trials with a larger sample size using XCM and comparing it to autogenous grafts in maxilla and mandible treating all types of recession defects with a longer period of follow up.